Le plan stratégique est mort, vive le plan culturel!

Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!

In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T helper (Th)1 and Th2 cells. Now we know that the reality is much more complex and interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows that the IL-17-related cytokine IL-25 is essential for Th2 responses in two infectious disease models.

Vive la science! Vive le hérisson!

The EMBO workshop 'Hedgehog Signalling: from Developmental Biology to Anti-cancer Drugs' took place between 27 and 31 March on the beautiful Côte d'Azur. The gathered scientists tackled topics ranging from the mechanisms by which Hedgehog (Hh) is presented to receptive cells, to the distribution of Hh by Glypicans, to the role of cilia in vertebrate Hh signal transduction, and to the function o...

Tests à la Hurewicz dans le plan

Le livre est tout le problème

The search into new ways of writing is confronted with certain obstacles, the foremost of which is that of the book and its conventions inherited from 536 years of existence. Yet, literature is by in large independent of the particular medium that is the book, as reminds us the age-old oral tradition or the contemporary research of the Oulipo. The incursion of the computer into literature has t...

Vive le (evidence-based practice) revolution.

I’m sure there is no one reading this article who is unfamiliar with the name, Cochrane, but you may be surprised to learn that behind the brand is an international network of more than 31,000 dedicated volunteers from over 100 countries all working together to prepare, update, and promote Cochrane systematic reviews. There are now over 5,000 Cochrane systematic reviews and they have become the...